Actos Attorney News – 3/15/2012: If you were prescribed Actos and have suffered negative side effects, please contact us today so that we can put you in touch with an attorney to advise you of your legal rights.

Actos Attorney: Bladder cancer, or any serious potentially life threatening illness is generally alien to most individuals. Suddenly, lives are changed and a new reality must be dealt with. Becoming a “patient” or worse “a cancer patient” is not only threatening, but a dreaded proposition. Cancer patients are not happy with the loss of autonomy, the invasion of privacy, the discomfort inflicted upon them and the demands on their time and quality of life. As a patient, being thrust into this altered identity, it is essential to seek out the information you need. Having a fundamental base of knowledge is a must when facing the issues and treatment decisions which lie ahead. In the following pages, together we will explore bladder cancer, a disease which is totally foreign to most of us until the diagnosis is made.

The bladder is a hollow organ nestled in the lower abdomen that serves as a storage container for urine, the liquid waste produced by the kidneys. The inner tissue of the bladder is surrounded by an outer layer of muscle that tightens to increase the pressure in the bladder when one is about to pass urine, forcing the urine to pass from the bladder into the urethra (the flexible tube that carries urine from the bladder to the point of urination) and out of the body. Cancer that arises in the bladder is one of the most common malignancies in industrialized societies, yet it is not well understood in the communi­ty at large. We believe that it is time to provide a simple, non-medical explanation of this disease for people who have to deal with this illness either as patients or as caregivers.

Cancer can affect any part of the bladder. When bladder cancer is examined under a microscope, different types can be identified. Transitional cell cancer, which accounts for more than 90 percent of bladder cancers, begins in the innermost layer of bladder tissue and consists of cells of variable sizes and shapes. It is called “transitional” because it resembles some of the other patterns of cells that are found in bladder cancer and has been thought to be intermediate or transi­tional between some of them. Because of where it begins, it is also called urothelial cancer. Another pattern is squamous cell carcinoma, which starts in the flat cells that line the inside of the bladder and (under the microscope) closely resembles the appearance of the cells that make up the layers of skin. Adenocarcinoma begins in cells that have a gland like appearance and make mucus. Squamous cell carci­noma and adenocarcinoma are very uncommon.

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Actos Attorney: Cancer is not one disease; it is many diseases affecting parts of the human body. All cancers have one thing in common: Something has gone wrong in the way some of the body’s cells normally grow, divide, and die. When a cancer forms, the main problem is that some cells start to grow, slowly or quickly, in an uncontrolled fashion, and the usual switch-off mechanisms that stop cell growth don’t work prop­erly. The breakdown in the switch-off mechanisms may be caused by exposure to chemicals (for example, some of those found in cigarette smoke), radiation, or even rare types of virus infection. The extra cells may cluster and form a tumor. Cancer cells may invade and damage surrounding tissue. Cancer cells may also break away and spread through the body by entering the lymph or blood systems. Most blad­der cancers are treatable by techniques that kill them or remove them surgically as they sit 011 the inner surface of the bladder; others axe invasive (having burrowed into the wall of the bladder) or metastatic (having spread to other parts of the body), and treatment is thus more complicated.

Bladder cancer primarily affects those between the ages of 50 and 70, more often men than women, and more Caucasians than African Americans, Hispanics, or Asians. Smokers, ex-smokers, and those who have jobs that expose them to certain chemicals or environmental toxins are at high risk of developing bladder cancer. Family members of those who have had bladder cancer are at slightly higher risk of developing the disease, and if you have already had bladder cancer, you have an increased chance of getting it again. The bladder is a balloon-shaped, muscular organ tucked into the pelvis and held in place by fibrous bands and muscle. The bladder is part of a system that includes the kidneys, ureters, and urethra. These work to process the waste products left behind after your body has taken out the nutrients it needs from the food you eat. The bladder is lined on the inside by a tissue known as “urothelium,” the smooth layer that stretches as the bladder fills and prevents excreted material from being reabsorbed into the body. Underneath the urothelium is a mix of fibrous or supporting tissue and muscle, both of which help the bladder to expand (when full) and to contract and excrete urine at the appropriate time.

The most common symptom of bladder cancer is hematuria, or blood visible in the urine, either with or without any accompanying pain. About 85 percent of the people diagnosed with bladder cancer notice blood in their urine, and it’s often what prompts them to seek med­ical attention. In some cases, the presence of blood isn’t noticeable to the naked eye and can only be seen through a microscope, usually when a urine test is being done during a routine physical or when an infection of the urinary tract or bladder is suspected. A urine test can detect whether blood is present in the urine and can also rule out whether other things, such as food or medicines, are the cause of red or rusty-colored urine.

Our use of the term or terms Actos Attorney is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

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Actos Lawyers News (01/23/2012):  Actos Lawyers are familiar with very serious concerns regarding the medication Actos.   Actos has been prescribed as part of a treatment regimen for controlling blood sugar in diabetic patients.  The U.S. Food and Drug Administration released a Safety Communication stating that use of Actos for a prolonged period of time may be associated with an increased risk of bladder cancer.  There are also other side effects that could require the expertise of Actos Lawyers.   These Actos Lawyers can discuss your legal rights to financial compensation and determine the strength of your claim.  Contact Best Legal Source at 800-611-7080 or complete the form to the right and we will put you in touch with a team of experienced Actos Lawyers.
 

 
Because of an increased risk of bladder cancer, contact your healthcare provider right away if you notice any of the following symptoms, such as blood in urine, frequent and painful urination and urinary tract infections.  Actos Lawyers can assist individuals who have suffered from these symptoms of bladder cancer after taking Actos.  Financial compensation for hospital and medical bills, along with loss of your health, may be recovered by speaking with one of our Actos Lawyers.
 
Actos Lawyers and Actos lawsuits are general terms used to describe the legal process provided by a lawyer experienced with Actos lawsuits and similar cases.  The use of these terms does not imply a connection between Best Legal Source and the manufacturers of Actos.  This website was created for the purpose of assisting those who have suffered as a result of taking this medication.  Call us today to connect with Actos Lawyers willing to help you recover any monetary damages.
 
If you believe you could have an Actos claim, get in touch with Actos Lawyers who will help you through the complexities of the legal process.  Get the compensation and the peace of mind you deserve by having these experienced lawyers working for you.  You have nothing to lose and everything to gain!  Call Best Legal Source today and be put in touch with qualified Actos Lawyers to discuss your legal options.
 

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Actos Lawyer:  Ultrasonography can check for a kidney tumor, stone, or obstruction. Bladders filled with urine can be scanned. There is no contrast or X rays involved, and therefore the study can be accomplished in those with renal disease, contrast allergies or for women who are pregnant. Although larger tumors of the bladder are often visible, it is not a good study to rule out urothelial cancer (transitional cell cancer of the urinary tract lining) since smaller tumors or flat tumors in the lining are not visible. Also, other conditions such as enlarged folds in the bladder or enlarged prostates can be confused with bladder tumors. Ultrasound exams are generally fast, painless, and relatively inexpensive. An ultrasound combined with cystoscopy plus cytology (to rule out cancer cells) is a reasonable assessment for those with a low likelihood of having upper tract disease.

CT Scan or CAT (computerized axial tomography) provides a computerized cross sectional visualization of the abdomen and pelvis. X ray images are synthesized into exquisitely detailed images. The CT scan can be done with or without IV contrast, and therefore has the same limitations as IVP in those with allergies to contrast or renal insufficiency. These studies are excellent for finding renal cell cancers and stones within the kidneys and ureter, but not very good at delineating cancers of the lining. CT scan is often an important part of staging bladder cancer, determining whether the cancer has spread.

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Magnetic Resonance Imaging (MRI) is a technology which uses strong magnets to provide detailed images of your internal organs. Like ultrasound, this study has no known harmful effects on the body. It does not require contrast injection like CT scan and can be done safely in patients with renal insufficiency. It is not generally used for initial screening. Many individuals find the test uncomfortable due to a loud noise heard throughout the test, in addition to the close quarters the machine requires, leading to feelings of claustrophobia. A mild sedative may be required if the test is necessary and the individual experiences these uncomfortable feelings.

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In the case of bladder cancer, initial stage is critical in predicting the prognosis. For individuals with bladder cancer, recurrence (repeated tumors) is common. For many, progression (the development of higher grade, invasive or metastatic cancer) is also a real concern. By looking at the initial stage of the bladder cancer and restaging with each new cancer recurrence, the urologist can predict or prognosticate the possibility of the individual developing more life threatening invasive disease which has the ability to spread beyond the bladder and lead to death. Treatment options exist at each stage of cancer. It is the goal of the urologist to preserve your bladder as long as possible without jeopardizing your life with a cancer that may spread and become incurable.

Our use of the term or terms Actos Lawyer is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

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Actos Lawyer:  The cystoscope may be attached to a camera so images appear on a video screen. This technology will allow your urologist to actually show you the findings during the examination. I have found many patients are at first hesitant to “view their insides,” but later thank me afterwards for having the opportunity. They often view the images with fascination and curiosity.

After cystoscopy, you should drink plenty of water, especially if there is some bleeding present. Mild discomfort generally lasts approximately 24 hours. It is not unusual to have some bleeding after cystoscopy, which is often the case if biopsies have been done. If you have had biopsies or a tumor has been resected, your urologist should give you specific instructions on what to avoid. Generally, it is best not to partake in heavy exercise or exertion. Avoid getting constipated as straining can start bleeding. You should call your urologist if you have persistent or severe pain afterwards, heavy bleeding (dark bloody urine or clots), persistent bleeding lasting more than a few days, inability to urinate, or a fever (temperature greater than 100 degrees Fahrenheit).

Urinary cytology is the examination of urine using special stains to look for cancer cells. These cells would have been those that have broken off (exfoliated) from the lining of the urinary tract. Voided urine is sent for analysis. First voided morning urine should not be used as there is a higher rate of cellular degeneration. To enhance the yield of cells, the bladder can be barbotaged (flushed). Cytology is most useful for high grade or aggressive tumors and for those with carcinoma in situ (CIS). In low to intermediate grade tumors, cytology may not be positive because these tumors may not exfoliate cells into the urine. In addition, if low grade tumor cells are exfoliated, they may appear to the pathologist to be identical to normal bladder cells. Due to the limitations of sensitivity of cytology, it is not a very good screening test, but proves to be valuable in following some individuals who have already been diagnosed and treated for bladder cancer.

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Because a positive cytology is very specific for cancer, it is highly predictive of transitional cell cancer even if no tumor is visible during cystoscopy. Additional information can be obtained with urine cytology. The DNA content and measurement of the amount of abnormal DNA can be determined. In general, as the amount of abnormal DNA is increased, the prognosis is worsened.  When an individual has gross hematuria or persistent microscopic hematuria, a complete assessment of the urinary tract is required. Although cystoscopy is the test of choice for examination of the bladder, imaging studies are required to make sure there is no disease in the upper tracts (kidneys and ureters). Bleeding can be caused from many different disorders including transitional cell carcinoma of the upper tracts, kidney or ureteral stones, or renal cell carcinoma (cancer of the parenchyma or fleshy part of the kidneys). Your urologist has a number of options to choose from. There are advantages and disadvantages of each.

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Intravenous pyelogram (IVP) is accomplished by injecting a contrast agent into your vein and then obtaining X ray images. The contrast is excreted by your kidneys, subsequently filling the lumen of the kidneys, ureters and the bladder. The contrast allows one to see subtle filling defects within chambers of the urinary tract, possibly representing tumor, stone or blood clot. Tumors of the fleshy part of the kidneys can also be seen. The study also allows for an assessment of renal function. It is a sensitive test for renal obstruction, which can occur because of cancer. Disadvantages of the study include the possibility of an IV contrast agent allergy, which occasionally may be serious.

You will be asked whether you have a sea food allergy, a known allergy to iodine or to IV contrast. If this is the case, you may need to be premedicated prior to the exam to avoid a reaction. Although the study is quite useful at visualizing the upper tracts, it is not very good at picking up subtle tumors on the bladder surface. If your kidneys do not function well (you have renal insufficiency), the contrast may cause harm to your kidneys and the imaging will not be as good. For pregnant women, any X ray exam could be potentially damaging to the fetus and therefore, will not be performed.

Our use of the term or terms Actos Lawyer is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

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Actos Lawyers 12/27/2011:   Men are at much higher risk for bladder cancer than women, although its not known why; it strikes men three to four times as often as it does women. The American Cancer Society projects that men have a 1 in 27 chance of develop­ing bladder cancer, while women have a 1 in 84 chance. The good news is that overall death rates for bladder cancer are decreasing for both men and women.

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Our use of the terms Actos Side Effects, Actos Lawsuit is not intended to imply or insinuate that their is any relationship or connection between Best Legal Source and the maker of Actos. Actos is a trademark of its manufacturer, Takeda Pharmaceutical Company Limited. Best Legal Source is not the maker of Actos nor do we have any connection with Takeda Pharmaceutical Company Limited.

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Actos Lawyers 12/27/2011:  Bladder cancer does not produce many symptoms, and many of the symptoms are typical of other, less severe con­ditions, such as infections or benign tumors. Besides blood in the urine, your symptoms can include pain or burning during urination, a feeling of having to urinate because of an uncomfortable fullness, or the need to get up frequently at night to urinate.

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Our use of the terms Actos Settlement, Actos Settlements is not intended to imply or insinuate that their is any relationship or connection between Best Legal Source and the maker of Actos. Actos is a trademark of its manufacturer, Takeda Pharmaceutical Company Limited. Best Legal Source is not the maker of Actos nor do we have any connection with Takeda Pharmaceutical Company Limited.

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Actos Lawyers 12/27/2011:  With the major symptoms of bladder cancer acting in such a variable fashion, appearing in different ways and sometimes disappearing altogether, it’s important to see your doctor immediately if you notice blood or what you think might be blood in your urine. As with most cancers, the key to successfully managing bladder cancer is detecting it early and starting treatment as soon as possible.

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Our use of the terms Actos Lawsuit, Actos FDA Recall  is not intended to imply or insinuate that their is any relationship or connection between Best Legal Source and the maker of Actos. Actos is a trademark of its manufacturer, Takeda Pharmaceutical Company Limited. Best Legal Source is not the maker of Actos nor do we have any connection with Takeda Pharmaceutical Company Limited.

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Actos Lawyers 12/27/2011:  The most common symptom of bladder cancer is hematu­ria, or blood visible in the urine, either with or without any accompanying pain. About 80 percent of the people diagnosed with bladder cancer notice blood in their urine, and its often what prompts them to seek medical attention. In some cases, the presence of blood isn’t noticeable to the naked eye and can only be seen through a microscope, usually when a urine test is being done during a routine physical or when an infection of the urinary tract or bladder is suspected. A urine test can detect whedier blood is present in the urine and can also rule out whether other things, such as food or medicines, are the cause of red or rusty-colored urine.

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Our use of the terms Actos Litigation,  Actos FDA Recall is not intended to imply or insinuate that their is any relationship or connection between Best Legal Source and the maker of Actos. Actos is a trademark of its manufacturer, Takeda Pharmaceutical Company Limited. Best Legal Source is not the maker of Actos nor do we have any connection with Takeda Pharmaceutical Company Limited.

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Actos Lawyers 12/27/2011:  A strong muscle somewhat like a rubber band encircles your bladder and keeps the urethra tightly closed until nerves in the bladder signal you that the bladder is full and it is time to urinate. Urinary problems include the inability to retain the urine in the normal fashion or to void urine from the body. Sometimes people experience the urge to urinate even if the bladder is not full. Sometimes this is caused by bacteria in the bladder, which can cause an infection called cystitis. This symptom can also be caused by local bladder irritation or by the development of cancer. Sometimes it is not even related to the bladder but an enlarged prostate, due to benign or cancerous causes.

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Our use of the terms Actos Lawyer, Actos Litigation  is not intended to imply or insinuate that their is any relationship or connection between Best Legal Source and the maker of Actos. Actos is a trademark of its manufacturer, Takeda Pharmaceutical Company Limited. Best Legal Source is not the maker of Actos nor do we have any connection with Takeda Pharmaceutical Company Limited.

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Actos Lawyer 12/27/2011:  Urea is filtered through the kidneys and, together with other waste by-products and water, is converted into urine. Urine is carried by thin tubes called ureters to the bladder, where it is stored. Muscles in the walls of th e ureters squeeze out small amounts of urine into the bladder on a constant basis, about every ten seconds. A healthy bladder can hold about two cups of urine for up to five hours. Healthy adults produce about six cups of urine a day.

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Our use of the terms Actos Lawyers, Actos Bladder Cancer Lawyer  is not intended to imply or insinuate that their is any relationship or connection between Best Legal Source and the maker of Actos. Actos is a trademark of its manufacturer, Takeda Pharmaceutical Company Limited. Best Legal Source is not the maker of Actos nor do we have any connection with Takeda Pharmaceutical Company Limited.

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